منابع مشابه
Genetic Testing for Alzheimer Disease
The following protocol contains medical necessity criteria that apply for this service. The criteria are also applicable to services provided in the local Medicare Advantage operating area for those members, unless separate Medicare Advantage criteria are indicated. If the criteria are not met, reimbursement will be denied and the patient cannot be billed. Please note that payment for covered s...
متن کاملGenetic epidemiology of Scheuermann's disease
BACKGROUND AND PURPOSE The genetic/environmental etiology of Scheuermann's disease is unclear. We estimated the heritability of the disease using an etiological model adjusted for sex and time of diagnosis, and examined whether the prevalence of Scheuermann's disease was constant over time. METHODS 46,418 twins were sent a questionnaire about health and disease. Of these, 75% returned the que...
متن کاملGenetic testing for early-onset Alzheimer disease.
The availability of testing for identified risk genes for Alzheimer disease (AD) in patients with clinically probable AD or their at-risk family members raises important questions for the neurologist. Because the potential benefits and risks of testing vary for each patient, physicians need to evaluate whether it is appropriate on a case-by-case basis. This article outlines the testing decision...
متن کاملAlzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers.
The global prevalence of dementia is as high as 24 million, and has been predicted to quadruple by the year 2050. In the US alone, Alzheimer disease (AD) - the most frequent cause of dementia characterized by a progressive decline in cognitive function in particular the memory domain - causes estimated health-care costs of $ 172 billion per year. Key neuropathological hallmarks of the AD brain ...
متن کاملThe genetic epidemiology of neurodegenerative disease.
Gene defects play a major role in the pathogenesis of degenerative disorders of the nervous system. In fact, it has been the very knowledge gained from genetic studies that has allowed the elucidation of the molecular mechanisms underlying the etiology and pathogenesis of many neurodegenerative disorders. In this review, we discuss the current status of genetic epidemiology of the most common n...
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ژورنال
عنوان ژورنال: Epidemiologic Reviews
سال: 1997
ISSN: 0193-936X,1478-6729
DOI: 10.1093/oxfordjournals.epirev.a017933